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Recent case reports, meta-analyses, and most recently, the breakthrough of 2 novel randomized controlled trials have shown DOACs to be a promising treatment for LV thrombus. Contrarily, some retrospective cohort reviews suggest less .
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These findings suggest that DOAC is non-inferior or at least as effective as warfarin in the treatment of left ventricular thrombus. These results are consistent with results seen in some prior retrospective studies, where safety and efficacy of DOAC was comparable to warfarin for SSE prevention [ 12 , 14 , 24 , 25 ].
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